USask livestock researchers awarded nearly $7 million

Investment from the province’s Agriculture Development Fund (ADF), supplemented by contributions from industry partners, will help researchers improve health and safety for animals, reduce the environmental impact of livestock farming, and provide promising researchers of tomorrow with invaluable experience.

“This major funding commitment from our partners supports agricultural research essential to food security in Saskatchewan, Canada, and the world,” said USask Vice-President, Research, Karen Chad. “This stellar livestock research helps increase agriculture value-added revenue, grow our agri-food exports, and address climate change, while training tomorrow’s skilled workers in this sector.”

The funding includes a $3.2-million investment in the USask Livestock and Forage Centre of Excellence (LFCE) for the management and operations of the world-class centre. Seven of the 20 USask research projects awarded ADF funding will be conducted all or in part at the LFCE, which has a mandate to improve the sustainability of the livestock and forage industries through research and education in five key areas: soil, forage and crop systems, cow management, feedlot operations, and alternative livestock including bison.

Projects announced Jan. 29 involving USask animal health research include:

• Developing a universal vaccine for influenza A in swine: Influenza A virus in swine is highly contagious, and has the potential to cause significant economic loss and to “jump” to humans. USask molecular biologist Yan Zhou at the Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac) will improve an existing vaccine so it can provide broad protection against all dominant strains of the virus in swine, increase production, and reduce costs, helping farmers across Saskatchewan and throughout North America.
• Tracking antimicrobial resistant E. coli in chickens: Infections in chickens caused by coli can kill up to 20 per cent of a flock, and are the leading cause of economic loss in the industry in Canada. Using whole genome sequencing, USask microbiologist and VIDO-InterVac scientist Aaron White will lead a research team to track and predict virulence and antimicrobial resistance in different strains of E. coli to better understand the cause of the infections. VIDO-InterVac scientist Jo-Anne Dillon and veterinary microbiologist Dr. Joe Rubin are part of the team.
• Testing for Salmonella dublin in dairy herds: Salmonella dublin, a commonly multiple-drug resistant variety of salmonella bacteria, poses significant risks to cattle health and is increasingly prevalent in western Canadian dairy operations. While infections in humans are rare, and associated with consuming unpasteurized milk products and undercooked meat, the symptoms can be severe — S. dublin causes more frequent and longer hospital stays than do other strains. USask cattle researchers Dr. Christopher Luby and Dr. Kamal Gabadage are aiming to improve existing testing methods to increase accuracy in identifying which cows carry the bacteria.

Examples of livestock research projects with potential to reduce environmental impact include:

• Using pea starch for swine feed: Increased global demand for pea protein has led to a surplus of pea starch, leftover from the extraction process. USask researcher Rex Newkirk, Saskatchewan Ministry of Agriculture Endowed Research Chair in Feed Processing Technology, will determine safe levels of the starch to include in pig feed to increase efficiency and help producers.
• Hybrid fall rye as a new forage source for beef cattle: Hybrid fall rye, a new crop developed in Germany, is a hardy winter crop with potential to dramatically increase yields, protect the environment, increase resistance to disease, and improve farmers’ bottom lines. USask cattle researcher Greg Penner will study the rye for suitability to feed cattle and inform producers of the results.
• Strategies to address mineral nutrition in the face of poor water quality: Sulfate-contaminated water is a major potential problem for livestock in Saskatchewan, causing nutrient deficiency and reproductive problems in cows. Penner has also been awarded an ADF grant to test whether supplementing cattle with the active ingredient in Pepto-Bismol or other dietary additives may be the solution.
• Reducing greenhouse gas emissions from cattle feedlots: USask engineering professor Terry Fonstad will determine the most environmentally friendly, efficient way to store, transport, and fertilize soil with cattle manure, examining the economics and total environmental footprint of various practices. Fonstad will also measure greenhouse gases in a closed cattle barn in order to compare different strategies.

The funding commitment also includes $375,000 to support 10 undergraduate summer research projects per year over five years. Co-ordinated by Dr. Elisabeth Snead with help from Saskatchewan Ministry of Agriculture scientists, the projects provide doctor of veterinary medicine students with exposure to both research and hands-on experience working with food animals and other animals important in agriculture, with the goal of making students more comfortable and confident dealing with these species during their professional careers after graduation.

Read a backgrounder from the Saskatchewan Ministry of Agriculture with details on all the projects.

The ADF program is supported through the Canadian Agricultural Partnership, a five-year $388-million investment by the federal and provincial governments in strategic initiatives for Saskatchewan agriculture.

Livestock research projects

The following researchers at the Western College of Veterinary Medicine (WCVM) have received ADF funding for their projects: 

Stocking density and feed bunk space as a risk factor for liver abscesses. Principal investigator: Dr. Diego Moya, Department of Large Animal Clinical Sciences, WCVM. ADF funding: $171,090. Saskatchewan Cattlemen's Association (SCA) funding: $20,000. 

Characterization and optimization of visual pen checking criteria to improve BRD treatment outcomes in feedlot cattle. Principal investigator: Dr. Diego Moya, Department of Large Animal Clinical Sciences, WCVM. ADF funding: $55,200.

Development of a modified live attenuated vaccine for broiler breeders to control variant infectious bursal disease. Principal investigator: Dr. Susantha Gomis, Department of Veterinary Pathology, WCVM. ADF funding: $150,000. 

Enhancing isolation of respiratory viruses from cattle and pigs for diagnostic, epidemiological investigation and applied use. Principal investigator: Dr. Matthew Loewen, Department of Veterinary Biomedical Sciences, WCVM. ADF funding: $92,780. 

Do novel neonatal calf prime and boost vaccine programs improve immunity and decrease respiratory disease at weaning? Principal investigator: Dr. Nathan Erickson, Department of Large Animal Clinical Sciences, WCVM. ADF funding: $62,000. SCA funding: $17,250. 

A screen for drugs that reveal Mycoplasma bovis to the bovine immune system. Principal investigator: Dr. Tony Ruzzini, Department of Veterinary Microbiology, WCVM. ADF funding: $218,200. SCA funding: $24,200. 

Molecular analysis of BRD-associated pathogen interactions. Principal investigator: Dr. Tony Ruzzini, Department of Veterinary Microbiology, WCVM. ADF funding: $70,000.

Development of a novel testing program for Salmonella enterica serovar dublin (Salmonella dublin) in dairy herds. Principal investigator: Dr. Chris Luby, Department of Large Animal Clinical Sciences, WCVM. ADF funding: $37,494. 

Experiential discovery and learning through research in food animal veterinary medicine. Principal investigator: Dr. Liz Snead, associate dean, research and graduate studies, WCVM. ADF funding: $375,000. 

Additional funding for ADF-funded project titled “Should livestock diet be tested for the levels of the epimers of ergot alkaloids? Are these epimers biologically active?" Principal investigator: Dr. Ahmad Al-Dissi, Department of Veterinary Pathology. ADF funding: $65,000. 

Genomic ASSETS (antimicrobial stewardship systems from evidence-based treatment strategies) for livestock. Principal investigator: Dr. Cheryl Waldner, Department of Large Animal Clinical Sciences. ADF funding: $788,477. SCA funding: $23,000. Feedlot Health Management Services: $439,184. 

The following researchers at Prairie Diagnostic Services (PDS) have received ADF funding for their livestock-related projects:

Understanding and controlling influenza D virus in cattle. Principal investigator: Dr. Yanyun Huang, CEO, PDS. ADF funding: $173,000. 

Genomic epidemiology of livestock production limiting diseases in Saskatchewan. Principal investigator: Dr. Anatoliy Trokhymchuk, PDS. ADF funding: $85,000. 

The following researchers at the Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac) have received ADF funding for their livestock-related projects:

Universal vaccine development for influenza a virus in swine. Principal investigator: Dr. Yan Zhou, VIDO-InterVac. ADF funding: $208,500. 

Using DNA sequencing to track and predict virulence and AMR in organisms that cause colibacillosis on Saskatchewan broiler farms. Principal investigator: Dr. Aaron White, VIDO-InterVac. ADF funding: $116,000.